Piotr Paneth

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email: piotr.paneth(at)p.lodz.pl

www: paneth.p.lodz.pl

phone: +48 42 631 3199

office: Room 114, Faculty of Chemistry, Zeromskiego 116


Research Interests:

Education:

Professor 1996
: President of the Republic of Poland
D.Sc. (habilitation) 1989: chemistry, Department of Chemistry, Technical University of Lodz, Poland Isotope effects on kinetically complex reactions
Ph.D. 1984 (with honors): chemistry, Department of Chemistry, Technical University of Lodz, Poland Oxygen and sulfur kinetic isotope effects on thermal isomerization of  bis(5,5-dimethyl-1,3,2,-dioxaphosphorinanyl); supervisor: prof. W Reimschüssel
M.Sc. 1976 (with honors): chemistry, Department of Chemistry, Technical University of Lodz, Poland Oxygen kinetic isotope effect on isomerization of monothiopyrophosphates; advisor:  prof. W Reimschüssel

Professional Experience:

2007 Visiting Professor, FIFC, University of Kyoto (1.5 month)

2006-2007 Visiting Professor, LAIEM CNRS UMR 6006 laboratory, Nantes, France (3 months)

2003 Visiting Professor, Department of Chemistry, Emerson Center, Emory University, Atlanta, GA (3 months)

2000-2001 Visiting Professor, Department of Chemistry, University of Minnesota, Minneapolis, MN, USA (9 months)

1998-1999 Visiting Professor, Department of Chemistry, University of Uppsala, Uppsala, Sweden (4 months)

1995 Visiting Professor, Department of Biochemistry, University of Nebraska, Lincoln, NE, USA (3 months)

1989-1992 Post-doctoral, Department of Biochemistry, University of Nebraska, Lincoln, NE, USA; with Marion H. O'Leary, Professsor and Head

1984-1986 Senior post-doctoral, Department of Chemistry, University of Wisconsin, Madison, WI, USA; with Marion H. O'Leary, Professor

Research grants/fellowships:

National Science Center (Maestro, 2012-2017), Binding isotope effects as new, unique tool for studies of receptor-ligand interactions

Polish-Swiss Joint Research Project (2011-2015), Novel stable isotope-based approaches for assessing the biodegradation of soil and groundwater contaminants

FP7 Maria Curie Action (ITN, 2010-2014), CSI: Environment—Isotope forensics meets biogeochemistry – linking sources and sinks of organic contaminants by compound specific isotope investigation


Honors and Awards:

2012 Collaborative scientific award from the Minister of Health

2012 Jan Zawidzki Medal awarded by the Polish Chemical Society

2011 NSF panelist in Chemistry, Washington, USA

2011-present Vice Chairman of the Scientific Board of the Center of Molecular and Macromolecular Studies, Polish Academy of Sciences, Lodz, Poland

2010-present Chairman of the Scientific Board, “Wiadomości Chemiczne” (“Chemical News”, in Polish), Warsaw

2010 Meritorious Service for Technical University of Lodz Award

2009 Collaborative scientific award from the Minister of Health

2009 Medal of the National Education Committee

2008 Scientific Award from the Rector of Medical University of Lodz

2007 JSPS Invitation Fellowship, Japan

2006 CNRS Visiting Fellowship, France

2000- 2001 Senior Fulbright Scholarship, Fulbright Foundation, Washington, U.S.A.

1998- 1999 The Visby Program Scholarship, Svenska Institutet, Sweden

1997 Silver Cross of Merrits, President of the Republic of Poland

1995 Group award (I degree) for scientific merrits from the Polish Society of Radiation Studies

1990 Individual award (III degree) for habilitation thesis from the Minister of National Education, (MEN), Poland

1985 Individual award (III degree) for doctoral thesis from the Minister of Science and Higher Education, (MNiSW), Poland

1976- present 23 awards for excellence in research and teaching from the Rector of Technical University of Lodz, Poland

Representative publications:

  1. K. Świderek, P. Paneth, Binding Isotope Effects, Chem. Rev. 113 2013 7851
  2. K. Świderek, P. Paneth, Extending Limits of Chlorine Kinetic Isotope Effects,  J. Org. Chem. 77 2012 5120
  3. A. Dybala-Defratyka, P. Adamczyk, P. Paneth, DFT Study of Trichloroethene Reaction with Permanganate in Aqueous Solution, Env. Sci. Technol. 45 2011 3006
  4. M. Wolfsberg, A. Van Hook, P. Paneth, Isotope Effects in the Chemical, Geological and Bio Sciences, Springer, London, 2010
  5. X. Li, L.W. Chung, P. Paneth and K. Morokuma, DFT and ONIOM(DFT:MM) Studies on Co-C Bond Cleavage and Hydrogen Transfer in B12-Dependent Methylmalonyl-CoA Mutase. Stepwise or Concerted Mechanism?  J. Am. Chem. Soc. 131 2009 5115
  6. K. Świderek, A. Panczakiewicz, A. Bujacz, G. Bujacz, P. Paneth, Modeling of isotope effects on binding oxamate to lactic dehydrogenase,  J. Phys Chem. B 113 2009 12782
  7. A. Dybala-Defratyka, L. Szatkowski, R. Kaminski, M. Wujec, A. Siwek, P. Paneth, Kinetic isotope effects on dehalogenation at an aromatic carbon,  Environ. Sci. Technol. 42 2008 7744
  8. A. Dybala-Defratyka, P. Paneth, R. Banerjee, D.G. Truhlar, Coupling of hydrogenic tunneling to active-site motion in the hydrogen radical transfer catalyzed by a coenzyme B12-dependent mutase, Proc. Natl. Acad. Sci. USA, 104 2007 10779
  9. P. Paneth, Chlorine Kinetic Isotope Effects on Enzymatic Dehalogenations, Acc. Chem. Res. 36 2003 120
  10. V. Anisimov, P. Paneth, ISOEFF98. A Program for Studies of Isotope Effects Using Hessian Modifications,  J. Mathem. Chem. 26 1999 75

Teaching:

Molecular modeling
Computational chemistry